Regeneration of Skin Surface by Multipotent Mesenchymal Stem Cells of Adipose Tissue in Laboratory Animals with Infected Wounds

Abstract

This paper presents results of experimental studies in laboratory animals with a simulated infected wound, for which mesenchymal stem cells (MSCs) derived from adipose tissue were used in its treatment. The following peculiarities of MSCs for regeneration of skin defects are established: faster arrest of inflammation, accelerated wound healing processes, as well as observed stimulation of growth of skin appendages. The results of this study may serve the basis for further research from development to introduction into clinical practice of cellular technologies for the treatment of infected wound of various etiologies. [Med-Science 2013; 2(2.000): 601-17]

Keywords

• regeneration
• infected wounds
• mesenchymal stem cells
• adipose tissue