Саратовский научно-медицинский журнал (Dec 2009)
Coorection Of Lipid Peroxydation And Antioxydant Protective System By Mexidol And Glycine In Patients With Acute Ethanol Intoxication
Abstract
The research goal is to study lipid peroxydation and ferments of antioxidant protection in group of patients with an acute alcohol intoxication and their correction by medicaments with antioxidant activity (mexidol, glycine and their combination). Patients with diagnosis of ethanol toxic action of moderate severity degree were under study. There were 4 groups - receiving standard therapy, standard therapy and glycine, standard therapy and mexidol, patients receiving standard therapy with combination of mexidol and glycine. Clinical condition and changes in system "lipid peroxidation - antioxidant protection» were estimated. The expressed improvement was revealed applying standard therapy with combination of mexidol and glycine