The present investigation aimed to evaluate the effect of Chitosan-Indole Butyric Acid (IBA) in the seed of Salicornia bigelovii under field conditions in Sonora, Mexico. During two vegetative cycles (2018/2019–2019/2020), cuttings of S. bigelovii were treated with 100 and 50% Chitosan from shrimp exoskeletons and indole butyric acid at 0.937 and 1.25 g·kg−1 and placed in basins under conditions of the Sonora desert, Mexico. Variables were measured: seed production, physicochemical analysis and lipid profile of the seed. The results affected significant increases (p −1. The results based on chitosan and IBA in cuttings, are a biostimulant in the morpho-physiology, yield production, and lipid content of S. bigelovii. Large-scale studies as a production system should be considered in further studies.