Interleukin 6 blockage-induced neutropenia in a patient with rheumatoid arthritis and resolved hepatitis B

Abstract

The authors present a case report of a 59-year-old woman with rheumatoid arthritis after documented recovery from hepatitis C (HCV) infection and with resolved HBV infection who has been undergoing successful tocilizumab treatment. The patient experienced moderate to severe neutropenia after consecutive tocilizumab administrations. However, no serious infections or HBV reactivation was recorded during that period.

Keywords

• hepatitis B
• neutropenia
• tocilizumab