STUDIES ON SPIROHETEROCYCLES : SYNTHESIS OF NEW SPIRO 4- THIAZOLIDINONES AS POSSIBLE BIODYNAMICS

Abstract

Spiro-4- thiazolidinones have been synthesized by the cyclocondensation of phthalazinyl hydrazones with cyclic ketones and substituted mercapto acetic acids. Compounds were screened for their antibacterial, antifungal and antihypertensive activity. The combined elemental analyses and spectroscopic data prove the authenticity of the synthesized compounds