Preliminary analysis of immune-related markers in thymic carcinoid

Jiaqi Zhang; Chao Guo; Lei Liu; Ke Zhao; Mengxin Zhou; Yeye Chen; Shanqing Li

doi:10.1186/s12967-023-04751-x

Journal of Translational Medicine (Dec 2023)

Preliminary analysis of immune-related markers in thymic carcinoid

Jiaqi Zhang,
Chao Guo,
Lei Liu,
Ke Zhao,
Mengxin Zhou,
Yeye Chen,
Shanqing Li

Affiliations

Jiaqi Zhang: Department of Thoracic Surgery, Peking Union Medical College Hospital, Chinese Academy of Medical Sciences and Peking Union Medical College
Chao Guo: Department of Thoracic Surgery, Peking Union Medical College Hospital, Chinese Academy of Medical Sciences and Peking Union Medical College
Lei Liu: Department of Thoracic Surgery, Peking Union Medical College Hospital, Chinese Academy of Medical Sciences and Peking Union Medical College
Ke Zhao: Department of Thoracic Surgery, Peking Union Medical College Hospital, Chinese Academy of Medical Sciences and Peking Union Medical College
Mengxin Zhou: Department of Thoracic Surgery, Peking Union Medical College Hospital, Chinese Academy of Medical Sciences and Peking Union Medical College
Yeye Chen: Department of Thoracic Surgery, Peking Union Medical College Hospital, Chinese Academy of Medical Sciences and Peking Union Medical College
Shanqing Li: Department of Thoracic Surgery, Peking Union Medical College Hospital, Chinese Academy of Medical Sciences and Peking Union Medical College

DOI: https://doi.org/10.1186/s12967-023-04751-x
Journal volume & issue: Vol. 21, no. 1
pp. 1 – 3

Abstract

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Abstract The immune-related microenvironment of thymic carcinoid has rarely been reported. We analyzed the expression of PD-L1 and VISTA, and the distribution of CD4+ T cells, CD8+ T cells and CD68+ macrophages in the thymic carcinoid by immunohistochemical staining, and showed the correlation between these markers and clinical survival, indicating the potential therapeutic prospects.

Published in Journal of Translational Medicine

ISSN: 1479-5876 (Online)
Publisher: BMC
Country of publisher: United Kingdom
LCC subjects: Medicine
Website: https://translational-medicine.biomedcentral.com/

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Abstract

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