The role of alternative polyadenylation in the antiviral innate immune response

Xin Jia; Shaochun Yuan; Yao Wang; Yonggui Fu; Yong Ge; Yutong Ge; Xihong Lan; Yuchao Feng; Feifei Qiu; Peiyi Li; Shangwu Chen; Anlong Xu

doi:10.1038/ncomms14605

Nature Communications (Feb 2017)

The role of alternative polyadenylation in the antiviral innate immune response

Xin Jia,
Shaochun Yuan,
Yao Wang,
Yonggui Fu,
Yong Ge,
Yutong Ge,
Xihong Lan,
Yuchao Feng,
Feifei Qiu,
Peiyi Li,
Shangwu Chen,
Anlong Xu

Affiliations

Xin Jia: Department of Biochemistry, State Key Laboratory of Biocontrol, School of Life Sciences, Sun Yat-Sen University
Shaochun Yuan: Department of Biochemistry, State Key Laboratory of Biocontrol, School of Life Sciences, Sun Yat-Sen University
Yao Wang: Department of Biochemistry, State Key Laboratory of Biocontrol, School of Life Sciences, Sun Yat-Sen University
Yonggui Fu: Department of Biochemistry, State Key Laboratory of Biocontrol, School of Life Sciences, Sun Yat-Sen University
Yong Ge: Department of Biochemistry, State Key Laboratory of Biocontrol, School of Life Sciences, Sun Yat-Sen University
Yutong Ge: Department of Biochemistry, State Key Laboratory of Biocontrol, School of Life Sciences, Sun Yat-Sen University
Xihong Lan: Department of Biochemistry, State Key Laboratory of Biocontrol, School of Life Sciences, Sun Yat-Sen University
Yuchao Feng: Department of Biochemistry, State Key Laboratory of Biocontrol, School of Life Sciences, Sun Yat-Sen University
Feifei Qiu: Department of Biochemistry, State Key Laboratory of Biocontrol, School of Life Sciences, Sun Yat-Sen University
Peiyi Li: Department of Biochemistry, State Key Laboratory of Biocontrol, School of Life Sciences, Sun Yat-Sen University
Shangwu Chen: Department of Biochemistry, State Key Laboratory of Biocontrol, School of Life Sciences, Sun Yat-Sen University
Anlong Xu: Department of Biochemistry, State Key Laboratory of Biocontrol, School of Life Sciences, Sun Yat-Sen University

DOI: https://doi.org/10.1038/ncomms14605
Journal volume & issue: Vol. 8, no. 1
pp. 1 – 12

Abstract

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RNA processing by alternative polyadenylation (APA) can result in 3′UTR diversity and regulation of target RNA function. Here the authors survey APA in viral infection of macrophages.

Published in Nature Communications

ISSN: 2041-1723 (Online)
Publisher: Nature Portfolio
Country of publisher: United Kingdom
LCC subjects: Science
Website: https://www.nature.com/ncomms/

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