You only waste twice: T cells in parasite-induced organ wasting
Felix Clemens Richter,
Andreas Bergthaler
Affiliations
Felix Clemens Richter
Institute of Hygiene and Applied Immunology, Department of Pathophysiology, Infectiology and Immunology, Medical University of Vienna, Vienna 1090, Austria; CeMM Research Center for Molecular Medicine of the Austrian Academy of Sciences, Vienna 1090, Austria
Andreas Bergthaler
Institute of Hygiene and Applied Immunology, Department of Pathophysiology, Infectiology and Immunology, Medical University of Vienna, Vienna 1090, Austria; CeMM Research Center for Molecular Medicine of the Austrian Academy of Sciences, Vienna 1090, Austria
In this issue of Cell Reports, Redford et al.1 uncouple the role of CD4+ and CD8+ T cells in controlling anorexia and wasting of muscle and adipose tissue during chronic parasitic infections. These results shed light on the impact of adaptive immune cells on organ catabolism.
