Review of factors in pterygium pathology

Yang Chen; Chao-Qun Wei; Yu Mi; Hong-Yan Ge

doi:10.3980/j.issn.1672-5123.2022.7.13

Guoji Yanke Zazhi (Jul 2022)

Review of factors in pterygium pathology

Yang Chen,
Chao-Qun Wei,
Yu Mi,
Hong-Yan Ge

Affiliations

Yang Chen: Eye Hospital, the First Affiliated Hospital of Harbin Medical University, Harbin 150001, Heilongjiang Province, China
Chao-Qun Wei: Eye Hospital, the First Affiliated Hospital of Harbin Medical University, Harbin 150001, Heilongjiang Province, China
Yu Mi: Eye Hospital, the First Affiliated Hospital of Harbin Medical University, Harbin 150001, Heilongjiang Province, China
Hong-Yan Ge: Eye Hospital, the First Affiliated Hospital of Harbin Medical University, Harbin 150001, Heilongjiang Province, China

DOI: https://doi.org/10.3980/j.issn.1672-5123.2022.7.13
Journal volume & issue: Vol. 22, no. 7
pp. 1133 – 1136

Abstract

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Pterygium is an ocular surface disease formed by many factors and associate with a series of changes caused by ultraviolet irradiation and radiation, its pathogenesis is still uncertain. Elevated vascular endothelial growth factor(VEGF), inflammatory infiltrates, angiogenesis, oxidative stress, epithelial-mesenchymal cell transition(EMT), and tumor suppressor gene inactivation are currently recognized causes of pterygium. The mechanism of this factor in pterygium deveopment is still not completely understood. This review aimed to investigate the role of these factors in pterygium formation and provide targeted therapy and effective preventive measures for clinical diagnosis and treatment.

Published in Guoji Yanke Zazhi

ISSN: 1672-5123 (Print)
Publisher: Press of International Journal of Ophthalmology (IJO PRESS)
Country of publisher: China
LCC subjects: Medicine: Ophthalmology
Website: http://ies.ijo.cn/

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Abstract

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