Perfluorodecalin-based oxygenated emulsion as a topical treatment for chemical burn to the eye

Sanming Li; Kunpeng Pang; Shuyan Zhu; Kathryn Pate; Jia Yin

doi:10.1038/s41467-022-35241-1

Nature Communications (Nov 2022)

Perfluorodecalin-based oxygenated emulsion as a topical treatment for chemical burn to the eye

Sanming Li,
Kunpeng Pang,
Shuyan Zhu,
Kathryn Pate,
Jia Yin

Affiliations

Sanming Li: Schepens Eye Research Institute of Massachusetts Eye and Ear, Harvard Medical School, Department of Ophthalmology
Kunpeng Pang: Schepens Eye Research Institute of Massachusetts Eye and Ear, Harvard Medical School, Department of Ophthalmology
Shuyan Zhu: Schepens Eye Research Institute of Massachusetts Eye and Ear, Harvard Medical School, Department of Ophthalmology
Kathryn Pate: Coruna Medical, LLC
Jia Yin: Schepens Eye Research Institute of Massachusetts Eye and Ear, Harvard Medical School, Department of Ophthalmology

DOI: https://doi.org/10.1038/s41467-022-35241-1
Journal volume & issue: Vol. 13, no. 1
pp. 1 – 14

Abstract

Read online

Chemical injuries to the eye are medical emergencies with limited acute treatment options and can cause permanent vision loss. Here, the authors show that perfluorodecalin-based supersaturated oxygen emulsion is a safe and effective topical therapeutic in treating acute ocular chemical burn by reducing tissue hypoxia and inflammation.

Published in Nature Communications

ISSN: 2041-1723 (Online)
Publisher: Nature Portfolio
Country of publisher: United Kingdom
LCC subjects: Science
Website: https://www.nature.com/ncomms/

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