Molecules (Sep 2022)

A Supramolecular Approach to Antimicrobial Surfaces

  • Valentina Gazzola,
  • Pietro Grisoli,
  • Valeria Amendola,
  • Giacomo Dacarro,
  • Carlo Mangano,
  • Piersandro Pallavicini,
  • Antonio Poggi,
  • Silvia Rossi,
  • Barbara Vigani,
  • Angelo Taglietti

DOI
https://doi.org/10.3390/molecules27175731
Journal volume & issue
Vol. 27, no. 17
p. 5731

Abstract

Read online

In this paper, we report on the preparation of Imidazole-functionalized glass surfaces, demonstrating the ability of a dinuclear Cu(II) complex of a macrocyclic ligand to give a “cascade” interaction with the deprotonated forms of grafted imidazole moieties. In this way, we realized a prototypal example of an antimicrobial surface based on a supramolecular approach, obtaining a neat microbicidal effect using low amounts of the described copper complex.

Keywords