LYMPHOCYTE SUBSETS, IMMUNOGLOBINS AND HUMAN LEUCOCYTE ANTIGENS OF 1-ST CLASS IN PATIENTS WITH ENDOMETRIOSIS

Abstract

We examined lymphocyte subsets, levels of A, M, G immunoglobulins and Human leucocyte antigens of I-st class (A, B) in 90 patients with endometriosis. The most significant decrease of CD3+, CD4+ lymphocytes number, immunoregulatory index (CD4+/CD8+), increase of levels of immunoglobulins A, G, M was determined in patients with endometriosis at the length of disease up to 3 years. Endometriosis was associated with А28, В5, В16, В37, В41 Human leucocyte antigens. HLA-antigens А32, В44, В61 were found in endometriosis women only.

Keywords

• endometriosis
• lymphocyte subsets
• immunoglobulins
• human leucocyte antigens