F1000Research (Jan 2022)

skater: an R package for SNP-based kinship analysis, testing, and evaluation [version 1; peer review: 2 approved, 1 approved with reservations]

  • Bruce Budowle,
  • Carlos Acevedo,
  • Shakeel Jessa,
  • August E. Woerner,
  • Jianye Ge,
  • Stephen D. Turner,
  • Matthew Scholz,
  • V.P. Nagraj

Journal volume & issue
Vol. 11

Abstract

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Motivation: SNP-based kinship analysis with genome-wide relationship estimation and IBD segment analysis methods produces results that often require further downstream process- ing and manipulation. A dedicated software package that consistently and intuitively imple- ments this analysis functionality is needed. Results: Here we present the skater R package for SNP-based kinship analysis, testing, and evaluation with R. The skater package contains a suite of well-documented tools for importing, parsing, and analyzing pedigree data, performing relationship degree inference, benchmarking relationship degree classification, and summarizing IBD segment data. Availability: The skater package is implemented as an R package and is released under the MIT license at https://github.com/signaturescience/skater. Documentation is available at https://signaturescience.github.io/skater.

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