Recent advances in the development of multiplexed nanophotonic biosensors.

Z.K.S. Mcotshana; L.N. Thwala; M.H.C. Tlomatsane; E. van Steen; P. Mthunzi-Kufa

Photodiagnosis and Photodynamic Therapy (Aug 2024)

Recent advances in the development of multiplexed nanophotonic biosensors.

Z.K.S. Mcotshana,
L.N. Thwala,
M.H.C. Tlomatsane,
E. van Steen,
P. Mthunzi-Kufa

Affiliations

Z.K.S. Mcotshana: National Laser Centre, Council for Scientific and Industrial Research, P.O. Box 395, Pretoria 0001, South Africa; Department of Chemical Engineering, University of Cape Town, South Ln, Rondebosch, Cape Town 7700, South Africa; Corresponding author.
L.N. Thwala: National Laser Centre, Council for Scientific and Industrial Research, P.O. Box 395, Pretoria 0001, South Africa
M.H.C. Tlomatsane: National Laser Centre, Council for Scientific and Industrial Research, P.O. Box 395, Pretoria 0001, South Africa; Department of Medical Virology, Department of Pathology, Faculty of Health Sciences, University of Cape Town, South Ln, Rondebosch, Cape Town 7700, South Africa
E. van Steen: Department of Chemical Engineering, University of Cape Town, South Ln, Rondebosch, Cape Town 7700, South Africa
P. Mthunzi-Kufa: National Laser Centre, Council for Scientific and Industrial Research, P.O. Box 395, Pretoria 0001, South Africa; College of Agriculture, Engineering and Science, School of Chemistry and Physics, University of Kwa-Zulu Natal, University Road, Westville, Durban 3630, South Africa

Journal volume & issue: Vol. 48
p. 104246

Abstract

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The field of nanophotonics has advanced and can be utilized as a method to detect different infectious diseases. The introduction of multiplex nanophotonic diagnostics has enabled the speedy and simultaneous detection of viral infections and specific biomarkers. The quick reaction times, high sensitivity, and specificity of multiplex nanophotonic diagnostics enable real-time identification of viruses without the need for nucleic acid amplification. This review presents an overview of nanophotonic tools used to identify diseases and particular biomarkers. The paper also examines possible research areas for the development of unique, cutting-edge multiplex nanophotonic diagnostics capable of concurrently detecting various diseases or biomarkers/biomolecules. Furthermore, it discusses barriers to further advancement and offers insight into anticipated trends.

Published in Photodiagnosis and Photodynamic Therapy

ISSN: 1572-1000 (Print); 1873-1597 (Online)
Publisher: Elsevier
Country of publisher: Netherlands
LCC subjects: Medicine: Medicine (General)
Website: https://www.sciencedirect.com/journal/photodiagnosis-and-photodynamic-therapy

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