Atlas of Regional Left Ventricular Scar in Nonischemic Cardiomyopathies

Annamaria Del Franco, MD, PhD; Roberta Ruggieri, MD; Maurizio Pieroni, MD; Michele Ciabatti, MD; Chiara Zocchi, MD; Giulia Biagioni, MD; Valentina Tavanti, MD; Stefano Del Pace, MD; Ornella Leone, MD; Stefano Favale, MD; Andrea Igoren Guaricci, MD; James Udelson, MD; Iacopo Olivotto, MD

JACC: Advances (Oct 2024)

Atlas of Regional Left Ventricular Scar in Nonischemic Cardiomyopathies

Annamaria Del Franco, MD, PhD,
Roberta Ruggieri, MD,
Maurizio Pieroni, MD,
Michele Ciabatti, MD,
Chiara Zocchi, MD,
Giulia Biagioni, MD,
Valentina Tavanti, MD,
Stefano Del Pace, MD,
Ornella Leone, MD,
Stefano Favale, MD,
Andrea Igoren Guaricci, MD,
James Udelson, MD,
Iacopo Olivotto, MD

Affiliations

Annamaria Del Franco, MD, PhD: Cardiomyopathy Unit, Careggi University Hospital, Florence, Italy; Address for correspondence: Dr Annamaria Del Franco, Cardiomyopathy Unit, Careggi University Hospital, Florence 50134, Italy.
Roberta Ruggieri, MD: UOC Cardiologia, Ospedale di Venere, Asl Bari, Bari, Italy
Maurizio Pieroni, MD: Cardiovascular Department, San Donato Hospital, Arezzo, Italy
Michele Ciabatti, MD: Cardiovascular Department, San Donato Hospital, Arezzo, Italy
Chiara Zocchi, MD: Cardiovascular Department, San Donato Hospital, Arezzo, Italy
Giulia Biagioni, MD: Cardiomyopathy Unit, Careggi University Hospital, Florence, Italy
Valentina Tavanti, MD: Radiology Department, San Donato Hospital, Arezzo, Italy
Stefano Del Pace, MD: Cardiothoracovascular Department, Careggi University Hospital, Florence, Italy
Ornella Leone, MD: Department of Pathology, Cardiovascular and Cardiac Transplant Pathology Unit, IRCCS Azienda Ospedaliero-Universitaria di Bologna, Bologna, Italy
Stefano Favale, MD: Cardiology Unit, Interdisciplinary Department of Medicine, University of Bari Aldo Moro, Bari, Italy
Andrea Igoren Guaricci, MD: Cardiology Unit, Interdisciplinary Department of Medicine, University of Bari Aldo Moro, Bari, Italy
James Udelson, MD: Division of Cardiology and The CardioVascular Center, Tufts Medical Center, and the Tufts University School of Medicine, Boston, Massachusetts, USA
Iacopo Olivotto, MD: Cardiomyopathy Unit, Careggi University Hospital, Florence, Italy; Cardiology Unit, Meyer University Hospital, Florence, Italy; Department of Experimental and Clinical Medicine, University of Florence, Florence, Italy

Journal volume & issue: Vol. 3, no. 10
p. 101214

Abstract

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Most acquired and inherited cardiomyopathies are characterized by regional left ventricular involvement and nonischemic myocardial scars, often with a disease-specific pattern. Irrespective of the etiology and pathophysiological mechanisms, myocardial disorders are invariably associated with cardiac fibrosis, which contributes to dysfunction and electrical instability. Accordingly, cardiac magnetic resonance plays a central role in the diagnostic work-up and prognostic risk stratification of cardiomyopathies, particularly with the increasing correlation between genetic background and specific disease phenotype. Starting from pattern and distribution of myocardial fibrosis at cardiac magnetic resonance, we provide a practical regional atlas of nonischemic myocardial scar to guide the diagnostic approach to nonischemic cardiomyopathies.

Published in JACC: Advances

ISSN: 2772-963X (Online)
Publisher: Elsevier
Country of publisher: United States
LCC subjects: Medicine: Internal medicine: Specialties of internal medicine: Diseases of the circulatory (Cardiovascular) system; Medicine: Internal medicine: Medical emergencies. Critical care. Intensive care. First aid
Website: https://www.sciencedirect.com/journal/jacc-advances

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