Real-time biomimetically monitoring superoxide anions released from transient transmembrane secretion to investigate the inhibition effect on Aspergillus flavus growth

Abstract

Aspergillus flavus (A. flavus) is a kind of ubiquitous pathgenic fungi, of which an early and accurate detection and inhibition mehtod is essential to reduce its resulted damage of Afatoxions. Here real-time monitoring superoxide anions (O2•−) released from cinnamaldehyde-treated A. flavus was performed for the first time by an electrochemical enzyme-free biomimetic O2•− sensor to offer not only a facile and reliable approach to monitor the effect of inhibiting methods against A. flavus growth, but also a highly sensitive analytical tool to detect A. flavus, thus holding great promise for the sensor to continuously real-time monitor A. flavus released from infection or/and contamination of food in A. flavus-related biological researches and clinic diagnosis of some fatal diseases.

Keywords

• Fungi
• Biomimetic enzymes
• Superoxide anion radical
• Biosensor
• Cinnamaldehyde