Nature Communications (Jul 2018)

APC2 controls dendrite development by promoting microtubule dynamics

  • Olga I. Kahn,
  • Philipp Schätzle,
  • Dieudonnée van de Willige,
  • Roderick P. Tas,
  • Feline W. Lindhout,
  • Sybren Portegies,
  • Lukas C. Kapitein,
  • Casper C. Hoogenraad

DOI
https://doi.org/10.1038/s41467-018-05124-5
Journal volume & issue
Vol. 9, no. 1
pp. 1 – 17

Abstract

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Microtubules in dendrites are characterized by mixed polarity orientation. Here, the authors show a role for adenomatous polyposis coli 2 (APC2) in regulating dendrite microtubule dynamics and dendrite development.