EEG Spectral Power Changes in Patients With Dysexecutive Syndrome Following Cognitive Intervention

Abstract

ABSTRACT Background Acquired brain injury (ABI) leads to cognitive deficiencies, alteration of brain activity associated with an increase in slow‐wave (delta and theta bands) power, and reduced fast‐wave (alpha, beta, and gamma bands) power. To compensate for the cognitive deficits that impact autonomy and quality of life, patients in a chronic phase can benefit from cognitive intervention. Objective This study explores the effects of cognitive intervention on brain activity, measured by electroencephalography (EEG), and on executive functioning, assessed by the Test of Attentional Performance (TAP) battery. Method We provided an ecological rehabilitation intervention, simulating real‐life tasks adapted for patients with chronic cognitive disorders. A single‐case experimental design (SCED) assessed patients' performance in terms of correct responses percentage (CRs) and reaction times (RTs), and EEG spectral powers before and 1 month after the intervention. The TAP tasks included working memory (WM), divided attention (DA), inhibition (GO), and flexibility (FL). EEG frequency powers were also measured during resting states. Results One month after the intervention, significant improvements were observed in CRs and RTs for the FL task. Increases in all frequency band powers occurred during FL, WM, and DA tasks, except for alpha bands in DA. In the GO task, delta and gamma power also increased after the intervention. No significant changes were found during resting‐state EEG. The results of this open study, without a control group, are preliminary. Conclusion The effects of the therapy are mostly reflected by changes in mental FL performance and altered EEG patterns during cognitive tasks, particularly in slow and fast‐frequency bands. We argue that cognitive intervention could amplify the compensatory mechanisms following brain damage and/or ease restoration mechanisms in the fast‐frequency activity bands. Further SCEDs or studies with control groups are needed to confirm these findings and the role of EEG biomarkers in rehabilitation.

Keywords

• acquired brain injury
• cognitive training
• EEG
• power spectral analysis