Remineralization of Dentine Caries Using Moringa Oleifera Based Nano-Silver Fluoride: A Single-Blinded, Randomized, Active-Controlled Clinical Trial

Abstract

Introduction: Dental caries is one of the most common chronic childhood diseases, and many decayed teeth remain untreated in underdeveloped and developing countries. This clinical trial aimed to evaluate the remineralization effect of Moringa oleifera-based nano-silver fluoride (NSF) on deciduous dentin caries Materials and Method: This study was a randomized, single-blinded clinical trial. A total of 138 teeth with carious lesions belonging to 83 children were selected and randomly assigned into three groups. Clinical evaluation was performed at 1 and 3 months after intervention. Results: The percentage of arrested caries within the groups were 86%, 42%, and 37% for NSF, MI varnish (GC, Japan), and FluoroDose varnish groups (Centrix Inc, USA), respectively. Results of 1 and 3 months follow-up period were same. Statistically significant difference was found between study groups (P < 0.001). Conclusion: The present study showed that M. oleifera-based NSF could be used for arresting dental caries when applied directly to the carious lesion.

Keywords

• clinical trial
• dental caries
• moringa oleifera
• nano-silver fluoride
• mi varnish (5% naf + 2% cpp-acp
• gc
• japan)
• fluorodose varnish (5% naf
• centrix inc
• usa)