Evaluation Iodine Status and Factors Associated with Low Urinary Iodine Level among Pregnant Women Who Received Iodine Supplementation during Pregnancy

Abstract

Objectives: To assess iodine status and factors associated with low urinary iodine level in women who received iodine supplementation during pregnancy.Materials and Methods: A prospective cross sectional study in term pregnant women admitted to labor room, Srinagarind Hospital, Khon Kaen University was implemented during May 2014 to December 2015. All 245 recruited women after completing the questionnaire for evaluating their knowledge, attitude and practice (KAP) of iodine consumption were asked to collect urine 5 - 10 ml. to assess urine iodine level. The information from their medical records was used to assess their obstetric history and medications during pregnancy. The good KAP was defined as six or higher from the full ten score. The urine iodine (UI) level <150 μg/L was categorized as low level. The microplate method was used to assess urine iodine levels by certified laboratory at Regional Health Promotion Center 7 Khon Kaen, Department of Health, Ministry of Public Health.Results: Almost all of women received daily iodine supplementation tablets, only 6 received iodized oil. Their median UI level was 182 μg/L and 35.5% had low UI level. Their mean KAP score was 4.9 (SD=1.9). There were 39.6% women with good KAP. The daily tablet of iodine supplementation side-effect was the only significant factor associated with low UI levels. Conclusion: Though the findings demonstrated the adequate median urine iodine level in pregnant women with the iodine supplementation, a substantial proportion of them still had low urine iodine level and need additional intervention.

Keywords

• Iodine deficiency
• iodine supplementation during pregnancy