WOMEN BLOOD COAGULATIVE SYSTEM INDICES IN PHYSIOLOGICAL PREGNANCY IN DEPENDENCE ON FETUS’ SEX

Abstract

Purpose: To study the features of the blood coagulation system of women at various stages of normal pregnancy, depending on the sex of the fetus.Material and Methods: Retrospective evaluation of blood coagulation in 259 women with physiological pregnancy in I, II and III trimester with no abnormalities of the blood was conducted. Of these, 116 women had female fetuses (I group), 143 - male fetuses (II group).Methods: The clinical, clinical laboratory, biochemical. Results: We found that with increasing gestational age the increased activity of coagulative hemostasis was noted in both clinical groups, but the rate of these changes was higher and reached a maximum in II trimester in women with a male fetus, whereas in women with female fetus pace of these changes was less pronounced.Summary: These results indicate the existence of differences in the «functional behavior» of individual components of the system of hemostasis in various stages of physiological pregnancy. In women with male fetuses we revealed higher coagulation readiness in physiological pregnancy, indicating the tension of coagulation system in this variant of sexual dimorphism.

Keywords

• physiological pregnancy
• blood coagulative system in pregnancy
• coagulation
• sexual dimorphism