Nicotinamide prevention in diabetes-induced alterations in the rat liver

Abstract

Objective. The study was performed to elucidate whether nicotinamide (NAm) can attenuate the diabetes-induced liver damage by correction of ammonia detoxifying function and disbalance of NAD-dependent processes in diabetic rats.

Keywords

• type 1 diabetes mellitus
• nicotinamide
• urea cycle
• nad+
• nad+/nadh ratio
• parp-1 gene
• parp-1