10-Hydroxy-<i>trans</i>-2-decenoic Acid, a New Potential Feed Additive for Broiler Chickens to Improve Growth Performance
Yuxin Zhang,
Shixia Geng,
Yuting Di,
Yongbo Sun,
Ying Liu,
Juntao Li,
Liying Zhang
Affiliations
Yuxin Zhang
State Key Laboratory of Animal Nutrition, Ministry of Agriculture and Rural Affairs Feed Industry Centre, China Agricultural University, Beijing 100193, China
Shixia Geng
State Key Laboratory of Animal Nutrition, Ministry of Agriculture and Rural Affairs Feed Industry Centre, China Agricultural University, Beijing 100193, China
Yuting Di
State Key Laboratory of Animal Nutrition, Ministry of Agriculture and Rural Affairs Feed Industry Centre, China Agricultural University, Beijing 100193, China
Yongbo Sun
State Key Laboratory of Animal Nutrition, Ministry of Agriculture and Rural Affairs Feed Industry Centre, China Agricultural University, Beijing 100193, China
Ying Liu
State Key Laboratory of Animal Nutrition, Ministry of Agriculture and Rural Affairs Feed Industry Centre, China Agricultural University, Beijing 100193, China
Juntao Li
State Key Laboratory of Animal Nutrition, Ministry of Agriculture and Rural Affairs Feed Industry Centre, China Agricultural University, Beijing 100193, China
Liying Zhang
State Key Laboratory of Animal Nutrition, Ministry of Agriculture and Rural Affairs Feed Industry Centre, China Agricultural University, Beijing 100193, China
The purposes of this study were to explore the potential possibility of 10-hydroxy-trans-2-decenoic acid (10-HDA) use in feeding broiler chickens. A total of 216 healthy 1-day-old chicks were divided into 2 treatments at random (diets supplemented with 0 or 40 mg/kg 10-HDA, respectively) with 6 replicates of 18 birds each, and were then reared for 42 days. The results found that a diet supplemented with 10-HDA significantly increased average daily gain of broiler chickens in d 22~42 and d 0~42. Compared with the control group, dietary inclusion of 10-HDA markedly increased the serum concentrations of immunoglobulin (Ig) G at d 21, as well as IgM and interleukin (IL)-10 at d 42, while decreasing the levels of tumor necrosis factor (TNF)-α at d 21, as well as IL-6, TNF-α, and IL-1β at d 42. Furthermore, broiler chickens fed a diet with 10-HDA had a higher (p < 0.05) serum activity of superoxide dismutase at d 42. Additionally, serum malondialdehyde content also decreased notably at d 21 and d 42. These results made it clear that 10-HDA increased the growth performance of broiler chickens, possibly by enhancing immune function and antioxidant capacity.
