Molbank (Jan 2023)

4-Amino-5-benzoyl-1-benzyl-2-(4,5,6,7-tetrahydro-1<i>H</i>-indol-2-yl)-1<i>H</i>-pyrrole-3-carbonitrile

  • Olga V. Petrova,
  • Igor A. Ushakov,
  • Lyubov N. Sobenina,
  • Victoriya V. Kireeva,
  • Boris A. Trofimov

DOI
https://doi.org/10.3390/M1547
Journal volume & issue
Vol. 2023, no. 1
p. M1547

Abstract

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The title compound, 4-amino-5-benzoyl-1-benzyl-2-(4,5,6,7-tetrahydro-1H-indol-2-yl)- 1H-pyrrole-3-carbonitrile, was synthesized for the first time in a 40% yield by the reaction of N-benzyl-3-imino-5,6,7,8-tetrahydro-3H-pyrrolo[1,2-a]indol-1-amine and 1-chloroacetophenone in a K2CO3/MeCN system (reflux, 6 h). The product was characterized by 1H-NMR, 13C-NMR, IR spectroscopy, and elemental analysis.

Keywords