Emerging Infectious Diseases (Oct 2019)

Antigenic Variation of Avian Influenza A(H5N6) Viruses, Guangdong Province, China, 2014–2018

  • Ru Bai,
  • Reina S. Sikkema,
  • Cong rong Li,
  • Bas B. Oude Munnink,
  • Jie Wu,
  • Lirong Zou,
  • Yi Jing,
  • Jing Lu,
  • Runyu Yuan,
  • Ming Liao,
  • Marion P.G. Koopmans,
  • Chang-wen Ke

DOI
https://doi.org/10.3201/eid2510.190274
Journal volume & issue
Vol. 25, no. 10
pp. 1932 – 1935

Abstract

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Market surveillance showed continuing circulation of avian influenza A(H5N6) virus in live poultry markets in Guangdong Province in 2017, despite compulsory vaccination for avian influenza A(H5Nx) and A(H7N9). We analyzed H5N6 viruses from 2014–2018 from Guangdong Province, revealing antigenic drift and decreased antibody response against the vaccine strain in vaccinated chickens.

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