Early disappearance of tumor antigen-reactive T cells from peripheral blood correlates with superior clinical outcomes in melanoma under anti-PD-1 therapy

• Thomas K Eigentler,
• Teresa Amaral,
• Benjamin Weide,
• Graham Pawelec,
• Tobias Sinnberg,
• Claus Garbe,
• Lukas Flatz,
• Friedegund Meier,
• Kilian Wistuba-Hamprecht,
• Alfred Königsrainer,
• Oltin T Pop,
• Jonas Bochem,
• Henning Zelba,
• Janine Spreuer,
• Andrea Gaissler,
• Karolin Thiel,
• Can Yurttas,
• Daniel Soffel,
• Stephan Forchhammer,
• Heike Niessner,
• Markus W Löffler

Affiliations

Thomas K Eigentler

Department of Dermatology, University Medical Center, Tübingen, Germany

Teresa Amaral

Department of Dermatology, University Medical Center, Tübingen, Germany

Benjamin Weide

Department of Dermatology, University Medical Center, Tübingen, Germany

Graham Pawelec

Health Sciences North Research Institute of Canada, Sudbury, Ontario, Canada

Tobias Sinnberg

Department of Dermatology, University Medical Center, Tübingen, Germany

Claus Garbe

Department of Dermatology, University Medical Center, Tübingen, Germany

Lukas Flatz

Department of Dermatology, University Medical Center, Tübingen, Germany

Friedegund Meier

Skin Cancer Center at the University Cancer Centre and National Center for Tumor Diseases Dresden; Department of Dermatology, Faculty of Medicine and University Hospital Carl Gustav Carus, Technische Universität Dresden, Germany

Kilian Wistuba-Hamprecht

Department of Dermatology, University Medical Center, Tübingen, Germany

Alfred Königsrainer

Department of General, Visceral and Transplant Surgery, University Hospital, Tübingen, Germany

Oltin T Pop

Institute for Immunobiology, Kantonsspital St. Gallen, St. Gallen, Switzerland

Jonas Bochem

Department of Dermatology, University Medical Center, Tübingen, Germany

Henning Zelba

Department of Dermatology, University Medical Center, Tübingen, Germany

Janine Spreuer

Department of Dermatology, University Medical Center, Tübingen, Germany

Andrea Gaissler

Department of Dermatology, University Medical Center, Tübingen, Germany

Karolin Thiel

Department of General, Visceral and Transplant Surgery, University Hospital, Tübingen, Germany

Can Yurttas

Department of General, Visceral and Transplant Surgery, University Hospital, Tübingen, Germany

Daniel Soffel

Department of Dermatology, University Medical Center, Tübingen, Germany

Stephan Forchhammer

Department of Dermatology, University Medical Center, Tübingen, Germany

Heike Niessner

Department of Dermatology, University Medical Center, Tübingen, Germany

Markus W Löffler

Department of General, Visceral and Transplant Surgery, University Hospital, Tübingen, Germany