Nature Communications (Jul 2022)

Duration of protection of CoronaVac plus heterologous BNT162b2 booster in the Omicron period in Brazil

  • Thiago Cerqueira-Silva,
  • Vinicius de Araujo Oliveira,
  • Enny S. Paixão,
  • Juracy Bertoldo Júnior,
  • Gerson O. Penna,
  • Guilherme L. Werneck,
  • Neil Pearce,
  • Maurício L. Barreto,
  • Viviane S. Boaventura,
  • Manoel Barral-Netto

DOI
https://doi.org/10.1038/s41467-022-31839-7
Journal volume & issue
Vol. 13, no. 1
pp. 1 – 6

Abstract

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Primary CoronaVac vaccination followed by a BNT162b2 booster dose confers protection against some SARS-CoV-2 variants but its effectiveness against Omicron is unknown. Here, the authors show that this combination confers a high level of protection against severe outcomes for up to 120 days, with evidence of waning for those aged 80 or older.