RNA expression profiling of peritoneal metastasis from pancreatic cancer treated with Pressurized Intraperitoneal Aerosol Chemotherapy (PIPAC)

Detlefsen Sönke; Burton Mark; Ainsworth Alan P.; Fristrup Claus; Graversen Martin; Pfeiffer Per; Tarpgaard Line S.; Mortensen Michael B.

doi:10.1515/pp-2024-0001

Pleura and Peritoneum (Jun 2024)

RNA expression profiling of peritoneal metastasis from pancreatic cancer treated with Pressurized Intraperitoneal Aerosol Chemotherapy (PIPAC)

Detlefsen Sönke,
Burton Mark,
Ainsworth Alan P.,
Fristrup Claus,
Graversen Martin,
Pfeiffer Per,
Tarpgaard Line S.,
Mortensen Michael B.

Affiliations

Detlefsen Sönke: Department of Pathology, Odense University Hospital, Odense, Denmark
Burton Mark: Department of Clinical Research, Faculty of Health Sciences, University of Southern Denmark, Odense, Denmark
Ainsworth Alan P.: Odense Pancreas Center (OPAC) and Odense PIPAC Center (OPC), Odense University Hospital, Odense, Denmark
Fristrup Claus: Odense Pancreas Center (OPAC) and Odense PIPAC Center (OPC), Odense University Hospital, Odense, Denmark
Graversen Martin: Odense Pancreas Center (OPAC) and Odense PIPAC Center (OPC), Odense University Hospital, Odense, Denmark
Pfeiffer Per: Odense Pancreas Center (OPAC) and Odense PIPAC Center (OPC), Odense University Hospital, Odense, Denmark
Tarpgaard Line S.: Odense Pancreas Center (OPAC) and Odense PIPAC Center (OPC), Odense University Hospital, Odense, Denmark
Mortensen Michael B.: Odense Pancreas Center (OPAC) and Odense PIPAC Center (OPC), Odense University Hospital, Odense, Denmark

DOI: https://doi.org/10.1515/pp-2024-0001
Journal volume & issue: Vol. 9, no. 2
pp. 79 – 91

Abstract

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Pressurized Intraperitoneal Aerosol Chemotherapy (PIPAC) is an experimental treatment option in peritoneal metastasis from pancreatic cancer (PM-PC). Aims were to examine mRNA profile of fibrosis due to response after systemic chemotherapy and PIPAC (Regression) compared to treatment-naïve PM-PC and chronic cholecystitis–related peritoneal fibrosis (Controls).

Published in Pleura and Peritoneum

ISSN: 2364-768X (Online)
Publisher: De Gruyter
Country of publisher: Germany
LCC subjects: Medicine: Internal medicine: Specialties of internal medicine
Website: https://www.degruyter.com/view/journals/pp/pp-overview.xml

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