Nature Communications (May 2020)

High residual carriage of vaccine-serotype Streptococcus pneumoniae after introduction of pneumococcal conjugate vaccine in Malawi

  • Todd D. Swarthout,
  • Claudio Fronterre,
  • José Lourenço,
  • Uri Obolski,
  • Andrea Gori,
  • Naor Bar-Zeev,
  • Dean Everett,
  • Arox W. Kamng’ona,
  • Thandie S. Mwalukomo,
  • Andrew A. Mataya,
  • Charles Mwansambo,
  • Marjory Banda,
  • Sunetra Gupta,
  • Peter Diggle,
  • Neil French,
  • Robert S. Heyderman

DOI
https://doi.org/10.1038/s41467-020-15786-9
Journal volume & issue
Vol. 11, no. 1
pp. 1 – 12

Abstract

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Impact of pneumococcal conjugate vaccines (PCV) in controlling carriage needs to be evaluated to inform vaccine policy. Here, Swarthout et al. show in a prospective rolling cross-sectional study in Malawi a high residual prevalence of vaccine-serotype S. pneumoniae 7 years after PCV introduction.