Recurrent RNA edits in human preimplantation potentially enhance maternal mRNA clearance

Affiliations

Yang Ding: Institute of Health Service and Transfusion Medicine
Yang Zheng: Institute of Health Service and Transfusion Medicine
Junting Wang: Institute of Health Service and Transfusion Medicine
Hao Li: Institute of Health Service and Transfusion Medicine
Chenghui Zhao: Medical Innovation Research Division of Chinese PLA General Hospital
Huan Tao: Institute of Health Service and Transfusion Medicine
Yaru Li: Institute of Health Service and Transfusion Medicine
Kang Xu: Institute of Health Service and Transfusion Medicine
Xin Huang: Beijing Institute of Radiation Medicine
Ge Gao: Biomedical Pioneering Innovation Center (BIOPIC), Beijing Advanced Innovation Center for Genomics (ICG), Center for Bioinformatics (CBI), and State Key Laboratory of Protein and Plant Gene Research at School of Life Sciences, Peking University
Hebing Chen: Institute of Health Service and Transfusion Medicine
Xiaochen Bo: Institute of Health Service and Transfusion Medicine

Abstract

An integrated analysis of RNA editing events in human embryo development suggests that recurrent RNA edits might enhance maternal mRNA clearance.