Reference interval and upper decission limit for serum uric acid – an evidence-based approach on Romanian population using an a posteriori method

Abstract

Introduction. There is accumulating evidence that high normal serum uric acid (SUA) levels of 6-7 mg/dL are associated with cardiovascular morbidity and metabolic syndrome (MetS), hence the need to redefine its upper limit of normal (ULN). We aimed to derive ULN based on statistics and evidence in a representative sample of the population and to observe its relation to MetS components.

Keywords

• hyperuricemia
• serum uric acid
• upper limit of normal
• reference intervals