Nature Communications (Dec 2020)
Cryo-electron tomography structure of Arp2/3 complex in cells reveals new insights into the branch junction
Abstract
The actin-related protein (Arp)2/3 complex nucleates branched actin filament networks pivotal for cell migration, endocytosis and pathogen infection. Here, authors report a 9.0 Å resolution structure of the actin filament Arp2/3 complex branch junction in cells using cryo-electron tomography and subtomogram averaging.