Nature Communications (Dec 2020)

A droplet microfluidic platform for high-throughput photochemical reaction discovery

  • Alexandra C. Sun,
  • Daniel J. Steyer,
  • Anthony R. Allen,
  • Emory M. Payne,
  • Robert T. Kennedy,
  • Corey R. J. Stephenson

DOI
https://doi.org/10.1038/s41467-020-19926-z
Journal volume & issue
Vol. 11, no. 1
pp. 1 – 6

Abstract

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Translating discovery scale vial-based batch reactions to continuous flow scale-up conditions is limited by significant time and resource constraints. Here, the authors report a photochemical droplet microfluidic platform, which enables high throughput reaction discovery in flow to generate pharmaceutically relevant compound libraries.