Case Reports in Dermatology (Nov 2020)

Drug Reaction with Eosinophilia and Systemic Symptoms (DRESS) Associated with Mycoplasma pneumoniae Infection

  • Guy Shalom,
  • Raed Khoury,
  • Amir Horev

DOI
https://doi.org/10.1159/000510706
Journal volume & issue
Vol. 12, no. 3
pp. 225 – 230

Abstract

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Mycoplasma infection may lower the threshold for drug allergy in particular patients. We present a case of drug reaction with eosinophilia and systemic symptoms (DRESS), with drug etiology and non-drug etiology (Mycoplasma infection). Possible synergism between previously known drug allergy and the acute Mycoplasma infection may have led to DRESS eruption. Interferon-γ release test and TNF-α release test yielded different patterns in the present case, suggesting a different role for each in different drug eruption types.

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