Cancer-associated thrombosis in Vietnam: Literature review and expert perspectives

Abstract

Cancer-associated thrombosis (CAT) is a substantial burden and an emerging topic of great interest in Vietnam. The management of CAT is complex, with several challenges, including a high risk of bleeding and thrombosis, treatment burden, and low treatment motivation due to the short life expectancy of patients. Another challenge in CAT management is the low awareness among local physicians regarding CAT. The introduction of direct oral anticoagulants, which offer a better risk–benefit profile compared to conventional anticoagulation, has brought about a revolution in CAT management. To address these challenges, a group of 14 experts, including cardiologists and oncologists, convened in January 2023 to discuss and provide comprehensive information on CAT management in Vietnam, along with recommendations to optimize clinical outcomes. This review will encompass the available evidence in the medical literature and the expert opinions derived from the meeting.

Keywords

• cancer-associated thrombosis
• non-vitamin k antagonist oral anticoagulants
• venous thromboembolism