mSystems
(Jun 2021)
Usnic Acid Treatment Changes the Composition of Mycobacterium tuberculosis Cell Envelope and Alters Bacterial Redox Status
Elwira Sieniawska,
Rafal Sawicki,
Wieslaw Truszkiewicz,
Andrey S. Marchev,
Milen I. Georgiev
Affiliations
Elwira Sieniawska
ORCiD Medical University of Lublin, Chair and Department of Pharmacognosy, Lublin, Poland
Rafal Sawicki
ORCiD Medical University of Lublin, Chair and Department of Biochemistry and Biotechnology, Lublin, Poland
Wieslaw Truszkiewicz
Medical University of Lublin, Chair and Department of Biochemistry and Biotechnology, Lublin, Poland
Andrey S. Marchev
Bulgarian Academy of Sciences, The Stephan Angeloff Institute of Microbiology, Laboratory of Metabolomics, Plovdiv, Bulgaria
Milen I. Georgiev
Bulgarian Academy of Sciences, The Stephan Angeloff Institute of Microbiology, Laboratory of Metabolomics, Plovdiv, Bulgaria
DOI
https://doi.org/10.1128/mSystems.00097-21
Journal volume & issue
Vol. 6,
no. 3
Abstract
Read online
The evaluation of mechanisms of mycobacterial response to natural products has been barely studied. However, it might be helpful to reveal bacterial adaptation strategies, which are eventually crucial for the discovery of new drug targets and, hence, understanding the resistance mechanisms.
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