PLoS ONE (Jan 2025)

Predictive factors for readmission due to neonatal hyperbilirubinemia: A retrospective case-control study.

  • Yueju Cai,
  • Xiaolan Li,
  • Ping Wang,
  • Yanyan Song

DOI
https://doi.org/10.1371/journal.pone.0320767
Journal volume & issue
Vol. 20, no. 4
p. e0320767

Abstract

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ObjectiveHyperbilirubinemia is a common cause of hospital readmission among neonates, but the factors contributing to post-discharge readmission remain unclear. Our study aimed to identify predictive factors associated with readmission for neonatal hyperbilirubinemia.MethodsThis retrospective case-control study included 421 neonates born at ≥ 35 weeks of gestation with hyperbilirubinemia between January and December 2021. The neonates were divided into a readmission group and a control group, and logistic regression was used to identify predictive factors associated with readmission.ResultsAmong the 421 neonates studied, 32 (7.6%) were readmitted. Logistic regression analysis identified preterm birth (ConclusionsProlonging hospitalization and implementing robust post-discharge monitoring may be essential for neonates with prematurity, ABO hemolysis, G6PD deficiency, or elevated TSB levels at discharge.