Southern African Journal of HIV Medicine (May 2016)

The end of the line? A case of drug resistance to third-line antiretroviral therapy

  • Theresa M. Rossouw,
  • Sonia Hitchcock,
  • Mariëtte Botes

DOI
https://doi.org/10.4102/sajhivmed.v17i1.454
Journal volume & issue
Vol. 17, no. 1
pp. e1 – e3

Abstract

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HIV drug resistance has been described in all antiretroviral drug classes and threatens the long-term success of HIV treatment. Here, we describe the first reported case of acquired resistance to the integrase strand transfer inhibitors in South Africa. This case illustrates the dilemma of treatment in the context of inadequate adherence and poor psychosocial support and highlights the potential risk of transmission of multidrug-resistant virus. Keywords: HIV drug resistance; third line

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