Cell Regeneration (Dec 2024)
Standard: Human gastric cancer organoids
- Ronghui Tan,
- Fan Hong,
- Ting Wang,
- Nanshan Zhong,
- Hongling Zhao,
- Rui-hua Xu,
- Lin Shen,
- Yingbin Liu,
- Xuebiao Yao,
- Dongxi Xiang,
- Dong Gao,
- Jianping Xiong,
- Lijian Hui,
- Bing Zhao,
- Zhifeng Miao,
- Jie Hao,
- Yong Li,
- Shijun Hu,
- Boqiang Fu,
- Guoqiang Hua,
- Lei Wang,
- Zhao-Lei Zeng,
- Chong Chen,
- Jianmin Wu,
- Changlin Wang,
- Chunnian Wang,
- Xianbao Zhan,
- Chen Song,
- Zhijian Sun,
- Chunping Yu,
- Yingying Yang,
- Gengming Niu,
- Yalong Wang,
- Tongbiao Zhao,
- Ye-Guang Chen
Affiliations
- Ronghui Tan
- Guangzhou National Laboratory
- Fan Hong
- Guangzhou National Laboratory
- Ting Wang
- The State Key Laboratory of Membrane Biology, Tsinghua‑Peking Center for Life Sciences,, School of Life Sciences , Tsinghua University
- Nanshan Zhong
- The MOE Basic Research and Innovation Center for the Targeted Therapeutics of Solid Tumors, School of Basic Medical Sciences, Jiangxi Medical College, Nanchang University
- Hongling Zhao
- Beijing Institute for Stem Cell and Regenerative Medicine
- Rui-hua Xu
- State Key Laboratory of Oncology in South China, Collaborative Innovation Center for Cancer Medicine, Sun Yat-Sen University Cancer Center
- Lin Shen
- State Key Laboratory of Holistic Integrative Management of Gastrointestinal Cancers, Department of Gastrointestinal Oncology, Beijing Key Laboratory of Carcinogenesis and Translational Research, Peking University Cancer Hospital & Institute
- Yingbin Liu
- State Key Laboratory of Systems Medicine for Cancer, Shanghai Cancer Institute, Shanghai Jiaotong University School of Medicine
- Xuebiao Yao
- MOE Key Laboratory of Cellular Dynamics, CAS Center for Excellence in Molecular Cell Science, University of Science and Technology of China
- Dongxi Xiang
- State Key Laboratory of Systems Medicine for Cancer, Shanghai Cancer Institute, Shanghai Jiaotong University School of Medicine
- Dong Gao
- Key Laboratory of Multi-Cell Systems, Shanghai Key Laboratory of Molecular Andrology, Center for Excellence in Molecular Cell Science, Shanghai Institute of Biochemistry and Cell Biology, Chinese Academy of Sciences
- Jianping Xiong
- Department of Oncology, The First Affiliated Hospital of Nanchang University
- Lijian Hui
- University of Chinese Academy of Sciences
- Bing Zhao
- The MOE Basic Research and Innovation Center for the Targeted Therapeutics of Solid Tumors, School of Basic Medical Sciences, Jiangxi Medical College, Nanchang University
- Zhifeng Miao
- Department of Surgical Oncology and General Surgery, The First Hospital of China Medical University
- Jie Hao
- National Stem Cell Resource Center, Institute of Zoology, Chinese Academy of Sciences
- Yong Li
- Department of Gastrointestinal Surgery, Department of General Surgery, Guangdong Provincial People’s Hospital (Guangdong Academy of Medical Sciences), Southern Medical University
- Shijun Hu
- Department of Cardiovascular Surgery of the First Affiliated Hospital & Institute for Cardiovascular Science, Collaborative Innovation Center of Hematology, State Key Laboratory of Radiation Medicine and Protection, Suzhou Medical College, Soochow University
- Boqiang Fu
- National Institute of Metrology
- Guoqiang Hua
- Department of Radiation Oncology and Cancer Institute, Fudan University Shanghai Cancer Center Fudan University
- Lei Wang
- Beijing Institute for Stem Cell and Regenerative Medicine
- Zhao-Lei Zeng
- State Key Laboratory of Oncology in South China, Collaborative Innovation Center for Cancer Medicine, Sun Yat-Sen University Cancer Center
- Chong Chen
- Gastric Cancer Centerand, Laboratory of Gastric Cancer, State Key Laboratory of Biotherapy, West China Hospital, Sichuan University
- Jianmin Wu
- Key Laboratory of Carcinogenesis and Translational Research (Ministry of Education), Center for Cancer Bioinformatics, Peking University Cancer Hospital & Institute
- Changlin Wang
- China National Institute of Standardization
- Chunnian Wang
- Department of Gastrointestinal Pathology, Ningbo Diagnostic Pathology Center
- Xianbao Zhan
- Department of Oncology, Changhai Hospital, Second Military Medical University
- Chen Song
- Huayi Regeneration Technology Co., Ltd
- Zhijian Sun
- K2 Oncology Co., Ltd
- Chunping Yu
- Lilly (China) Research and Development Center
- Yingying Yang
- Qilu Pharmaceutical Co., Ltd
- Gengming Niu
- Shanghai OneTar Biomedicine Co., Ltd
- Yalong Wang
- Guangzhou National Laboratory
- Tongbiao Zhao
- Beijing Institute for Stem Cell and Regenerative Medicine
- Ye-Guang Chen
- Guangzhou National Laboratory
- DOI
- https://doi.org/10.1186/s13619-024-00217-7
- Journal volume & issue
-
Vol. 13,
no. 1
pp. 1 – 7
Abstract
Abstract Gastric cancer is one of the most common malignancies with poor prognosis. The use of organoids to simulate gastric cancer has rapidly developed over the past several years. Patient-derived gastric cancer organoids serve as in vitro models that closely mimics donor characteristics, offering new opportunities for both basic and applied research. The “Human Gastric Cancer Organoid” is part of a series of guidelines for human gastric cancer organoids in China, jointly drafted by experts from the Chinese Society for Cell Biology and its branches, and initially released on October 29, 2024. This standard outlines terminology, technical requirements, assessment protocols, and applies to production, evaluation procedures, and quality control for human gastric cancer organoids. The publication of this guideline aims to assist institutions in endorsing, establishing, and applying best practices, advancing the international standardization of human gastric cancer organoids for clinical development and therapeutic application.
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