Functional impact of the head domain variants of DES (Desmin) on filament assembly

• Sabrina Voß,
• Volker Walhorn,
• Stephanie Holler,
• Anna Gärtner,
• Greta Pohl,
• Jens Tiesmeier,
• Jan Gummert,
• Dario Anselmetti,
• Hendrik Milting,
• Andreas Brodehl

Affiliations

Sabrina Voß

Erich and Hanna Klessmann Institute, Heart and Diabetes Center NRW, University Hospital of the Ruhr-University Bochum, Georgstrasse 11, Bad Oeynhausen D-32545, Germany

Volker Walhorn

Experimental Biophysics & Applied Nanoscience, Faculty of Physics, Bielefeld University, Universitätsstrasse 25, Bielefeld 33615, Germany

Stephanie Holler

Erich and Hanna Klessmann Institute, Heart and Diabetes Center NRW, University Hospital of the Ruhr-University Bochum, Georgstrasse 11, Bad Oeynhausen D-32545, Germany

Anna Gärtner

Erich and Hanna Klessmann Institute, Heart and Diabetes Center NRW, University Hospital of the Ruhr-University Bochum, Georgstrasse 11, Bad Oeynhausen D-32545, Germany

Greta Pohl

Erich and Hanna Klessmann Institute, Heart and Diabetes Center NRW, University Hospital of the Ruhr-University Bochum, Georgstrasse 11, Bad Oeynhausen D-32545, Germany

Jens Tiesmeier

Erich and Hanna Klessmann Institute, Heart and Diabetes Center NRW, University Hospital of the Ruhr-University Bochum, Georgstrasse 11, Bad Oeynhausen D-32545, Germany; Institute for Anesthesiology, Intensive Care- and Emergency Medicine, MKK-Hospital Luebbecke, Campus OWL, Ruhr-University Bochum, Virchowstrasse 65, Lübbecke 32312, Germany

Jan Gummert

Erich and Hanna Klessmann Institute, Heart and Diabetes Center NRW, University Hospital of the Ruhr-University Bochum, Georgstrasse 11, Bad Oeynhausen D-32545, Germany

Dario Anselmetti

Experimental Biophysics & Applied Nanoscience, Faculty of Physics, Bielefeld University, Universitätsstrasse 25, Bielefeld 33615, Germany

Hendrik Milting

Erich and Hanna Klessmann Institute, Heart and Diabetes Center NRW, University Hospital of the Ruhr-University Bochum, Georgstrasse 11, Bad Oeynhausen D-32545, Germany

Andreas Brodehl

Erich and Hanna Klessmann Institute, Heart and Diabetes Center NRW, University Hospital of the Ruhr-University Bochum, Georgstrasse 11, Bad Oeynhausen D-32545, Germany; Corresponding author.