Renal Involvement in COVID-19: A Review of the Literature

Abstract

Marco Giuseppe Migliaccio,1,* Marco Di Mauro,1,* Riccardo Ricciolino,1 Giorgio Spiniello,1 Vincenzo Carfora,1 Nicoletta Verde,1 Filiberto Fausto Mottola,1 Nicola Coppola2 On behalf of the Vanvitelli COVID-19 Group1Department of Translational Medical Sciences, University of Campania “Luigi Vanvitelli”, Naples, Italy; 2Department of Mental Health and Public Medicine, Infectious Diseases Unit, University of Campania “Luigi Vanvitelli”, Naples, Italy*These authors contributed equally to this workCorrespondence: Nicola CoppolaDepartment of Mental Health and Public Medicine, Infectious Diseases Unit, University of Campania “Luigi Vanvitelli”, Via: L. Armanni 5, Naples, 80131, ItalyTel [phone]Fax [phone]Email [email protected]: Kidney injury may be a severe complication of acute respiratory syndrome coronavirus 2 (SARS-CoV-2) and contributes to worsen the prognosis. Various pathophysiological mechanisms can contribute to organ damage and impair renal function, proving the complexity of the virus activity and the resulting immunity response. We summarized the evidence of the literature on the prevalence of kidney involvement, on the pathogenic pathways and on its management.Keywords: kidney injury, acute kidney injury, COVID-19, SARS-CoV-2

Keywords

• kidney injury
• acute kidney injury
• covid-19
• sars-cov-2