Monoclonal Antibodies in Oral Cancer Therapy

Abstract

With a fast growing group of medications in the therapeutic field, monoclonal antibodies (MAbs) have a wide range of current and potential therapeutic applications. Several efforts have been made to the development of human MAbs since antibodies of human origin are expected to be superior to others. This review focuses on the usage of MAbs in the treatment of oral cancer and their limitations. The literature search was done in various search engines such as Medline, PubMed, Wiley, Science Direct, and Scopus. The keywords used for the database search were immunotherapy, MAbs, and oral cancer therapy. A total of 80 articles appeared from various sources, of which 60 were subjected to screening and 36 were related to the research objective. Based on the literature search, it is evident that MAbs can be used for oral cancer management and is under clinical trials for future prospects.

Keywords

• biologics
• immunotherapy
• monoclonal antibodies
• oral cancer therapy