陆军军医大学学报 (Jul 2024)
Performance of aortic annulus diameter in diagnosis of T2DM with concomitant coronary heart disease
Abstract
Objective To investigate the performance of a common echocardiographic (ECG) indicator, aortic annulus diameter, in the diagnosis of type 2 diabetes mellitus (T2DM) complicated with coronary heart disease (CHD). Methods A cross-sectional study was conducted on the patients undergoing coronary angiography in Department of Cardiovascular Medicine of Affiliated Hospital of Xuzhou Medical University from October 1, 2022 to October 31, 2023. A total of 440 patients were included into a training set, including 217 with confirmed T2DM combined with CHD (T2DM-CHD group) and 223 patients with simple T2DM (control group). In a ratio of 7∶3, another 187 patients were selected and assigned into a validation group, including 91 T2DM-CHD patients and 96 T2DM patients. Their general clinical data and ECG indicators were collected, and the relationships of ECG indicators and coexistence of T2DM-CHD were analyzed. Receiver operating characteristic curve (ROC) was plotted to identify the best predictor for the coexistence with area under the curve (AUC), and the cutoff values and their accuracies in diagnosis were further determined and verified. Results Among all ECG indicators, only aortic sinus and aortic annulus diameter showed statistical differences between the T2DM-CHD group and the control group (P < 0.05). Significant correlations were observed between the above 2 indicators and the diagnostic types of the 2 groups (P < 0.05). The AUC value of aortic annulus diameter in predicting diagnostic types was 0.920 (P < 0.01), with a sensitivity of 0.819 and a specificity of 0.843, and the cutoff value was 23.00 mm, which had an accuracy of 90.37%. Conclusion Aortic annulus diameter is a pivotal predictor for identifying T2DM-CHD patients. The T2DM patients with aortic ring diameter < 23.00 mm are more common with concomitant CHD.
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