Immune regulation based on sex differences in ischemic stroke pathology

Pingping Niu; Pingping Niu; Liqin Li; Liqin Li; Yonggang Zhang; Yonggang Zhang; Zhongzhou Su; Zhongzhou Su; Binghao Wang; Binghao Wang; He Liu; Shehong Zhang; Sheng Qiu; Sheng Qiu; Yuntao Li; Yuntao Li

doi:10.3389/fimmu.2023.1087815

Frontiers in Immunology (Jan 2023)

Immune regulation based on sex differences in ischemic stroke pathology

Pingping Niu,
Pingping Niu,
Liqin Li,
Liqin Li,
Yonggang Zhang,
Yonggang Zhang,
Zhongzhou Su,
Zhongzhou Su,
Binghao Wang,
Binghao Wang,
He Liu,
Shehong Zhang,
Sheng Qiu,
Sheng Qiu,
Yuntao Li,
Yuntao Li

Affiliations

Pingping Niu: Department of Neurosurgery, The Affiliated Huzhou Hospital, Zhejiang University School of Medicine (Huzhou Central Hospital), Huzhou, China
Pingping Niu: Huzhou Key Laboratory of Basic Research and Clinical Translation for Neuro Modulation, Huzhou, China
Liqin Li: Department of Neurosurgery, The Affiliated Huzhou Hospital, Zhejiang University School of Medicine (Huzhou Central Hospital), Huzhou, China
Liqin Li: Huzhou Key Laboratory of Basic Research and Clinical Translation for Neuro Modulation, Huzhou, China
Yonggang Zhang: Department of Neurosurgery, The Affiliated Huzhou Hospital, Zhejiang University School of Medicine (Huzhou Central Hospital), Huzhou, China
Yonggang Zhang: Huzhou Key Laboratory of Basic Research and Clinical Translation for Neuro Modulation, Huzhou, China
Zhongzhou Su: Department of Neurosurgery, The Affiliated Huzhou Hospital, Zhejiang University School of Medicine (Huzhou Central Hospital), Huzhou, China
Zhongzhou Su: Huzhou Key Laboratory of Basic Research and Clinical Translation for Neuro Modulation, Huzhou, China
Binghao Wang: Department of Neurosurgery, The Affiliated Huzhou Hospital, Zhejiang University School of Medicine (Huzhou Central Hospital), Huzhou, China
Binghao Wang: Huzhou Key Laboratory of Basic Research and Clinical Translation for Neuro Modulation, Huzhou, China
He Liu: Huzhou Key Laboratory of Basic Research and Clinical Translation for Neuro Modulation, Huzhou, China
Shehong Zhang: Huzhou Key Laboratory of Basic Research and Clinical Translation for Neuro Modulation, Huzhou, China
Sheng Qiu: Department of Neurosurgery, The Affiliated Huzhou Hospital, Zhejiang University School of Medicine (Huzhou Central Hospital), Huzhou, China
Sheng Qiu: Huzhou Key Laboratory of Basic Research and Clinical Translation for Neuro Modulation, Huzhou, China
Yuntao Li: Department of Neurosurgery, The Affiliated Huzhou Hospital, Zhejiang University School of Medicine (Huzhou Central Hospital), Huzhou, China
Yuntao Li: Huzhou Key Laboratory of Basic Research and Clinical Translation for Neuro Modulation, Huzhou, China

DOI: https://doi.org/10.3389/fimmu.2023.1087815
Journal volume & issue: Vol. 14

Abstract

Read online

Ischemic stroke is one of the world’s leading causes of death and disability. It has been established that gender differences in stroke outcomes prevail, and the immune response after stroke is an important factor affecting patient outcomes. However, gender disparities lead to different immune metabolic tendencies closely related to immune regulation after stroke. The present review provides a comprehensive overview of the role and mechanism of immune regulation based on sex differences in ischemic stroke pathology.

Published in Frontiers in Immunology

ISSN: 1664-3224 (Online)
Publisher: Frontiers Media S.A.
Country of publisher: Switzerland
LCC subjects: Medicine: Internal medicine: Specialties of internal medicine: Immunologic diseases. Allergy
Website: http://journal.frontiersin.org/journal/immunology

About the journal

Abstract

Keywords