Nature Communications (Mar 2022)

Brain-wide projection reconstruction of single functionally defined neurons

  • Meng Wang,
  • Ke Liu,
  • Junxia Pan,
  • Jialin Li,
  • Pei Sun,
  • Yongsheng Zhang,
  • Longhui Li,
  • Wenyan Guo,
  • Qianqian Xin,
  • Zhikai Zhao,
  • Yurong Liu,
  • Zhenqiao Zhou,
  • Jing Lyu,
  • Ting Zheng,
  • Yunyun Han,
  • Chunqing Zhang,
  • Xiang Liao,
  • Shaoqun Zeng,
  • Hongbo Jia,
  • Xiaowei Chen

DOI
https://doi.org/10.1038/s41467-022-29229-0
Journal volume & issue
Vol. 13, no. 1
pp. 1 – 14

Abstract

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Brain-wide axonal projections of single neurons have been extensively reconstructed without any functional characterization. The authors present a method that allows for developing a precise one-to-one map of both projection patterns and functional features of single neurons in mice.