Zdorovʹe Rebenka (Aug 2014)

Some Markers of Liver Regeneration in Young Children with Congenital and Chronic Hepatitis

  • O.G. Shadrin,
  • O.O. Magomedov,
  • N.F. Chernega,
  • N.M. Basaraba,
  • S.V. Dyukareva,
  • A.A. Kovalchuk

DOI
https://doi.org/10.22141/2224-0551.5.56.2014.76237
Journal volume & issue
Vol. 9, no. 5.56
pp. 7 – 12

Abstract

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As a result of clinical and paraclinical studies in young children with hepatitis we detected increased concentration of hepatocyte growth factor (HGF) and tumor necrosis factor α, which indicates a high fibrous focus of inflammation in the liver, regardless of the duration of the course. Correlation between the levels of HGF and protein-bound hydroxyproline justifies the use of indicators as markers of the regenerative activity of the liver, the relationship between them increases with the duration of the pathological process.

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