BMC Cardiovascular Disorders (Nov 2022)

New insights into fibrous cap thickness of vulnerable plaques assessed by optical coherence tomography

  • Xianglan Liu,
  • Wujian He,
  • Xulin Hong,
  • Duanbin Li,
  • Zhezhe Chen,
  • Yao Wang,
  • Zhaoyang Chen,
  • Yi Luan,
  • Wenbin Zhang

DOI
https://doi.org/10.1186/s12872-022-02896-z
Journal volume & issue
Vol. 22, no. 1
pp. 1 – 8

Abstract

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Abstract Objective Vulnerable plaques with fibrous cap thickness (FCT) of ≤65 μm are prone to rupture and/or thrombosis. However, plaques with FCT > 65 μm cause acute myocardial infarction and even sudden death. We aimed to investigate the relationship between 65 80 μm, n = 271). Clinical and laboratory data was collected from the inpatient medical record system. Results Plaques with thinner FCT, especially 80 μm (P 80 μm]: OR = 8.082, 95% CI = 4.861 to 13.435, P 80 μm]: OR = 2.463, 95% CI = 1.370 to 4.430, P = 0.003), thrombosis ([FCT ≤ 65 μm vs. FCT > 80 μm]: OR = 25.224, 95% CI = 13.768 to 46.212, P 80 μm]: OR = 3.675, 95% CI = 2.065 to 6.542, P 80 μm]: OR = 22.593, 95% CI = 11.426 to 44.674, P 80 μm]: OR = 4.143, 95% CI = 1.869 to 9.184, P 80 μm.

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