Mesoporous biophotonic carbon spheres with tunable curvature for intelligent drug delivery
Fu Jianye,
Hui Tiankun,
An Dong,
Shan Wei,
Chen Guobo,
Wageh Swelm,
Al-Hartomy Omar A.,
Zhang Bin,
Xie Ni,
Nie Guohui,
Jiao Jinqing,
Qiu Meng,
Zhang Han
Affiliations
Fu Jianye
Key Laboratory of Marine Chemistry Theory and Technology (Ocean University of China), Ministry of Education, Qingdao, 266100, China
Hui Tiankun
Key Laboratory of Marine Chemistry Theory and Technology (Ocean University of China), Ministry of Education, Qingdao, 266100, China
An Dong
Collaborative Innovation Center for Optoelectronic Science & Technology, International Collaborative Laboratory of 2D Materials for Optoelectronics Science and Technology of Ministry of Education, College of Physics and Optoelectronic Engineering, Institute of Microscale Optoelectronics, Shenzhen University, Shenzhen518060, P. R. China
Shan Wei
Key Laboratory of Marine Chemistry Theory and Technology (Ocean University of China), Ministry of Education, Qingdao, 266100, China
Chen Guobo
Key Laboratory of Marine Chemistry Theory and Technology (Ocean University of China), Ministry of Education, Qingdao, 266100, China
Wageh Swelm
Department of Physics, Faculty of Science, King Abdulaziz University, Jeddah21589, Saudi Arabia
Al-Hartomy Omar A.
Department of Physics, Faculty of Science, King Abdulaziz University, Jeddah21589, Saudi Arabia
Zhang Bin
Collaborative Innovation Center for Optoelectronic Science & Technology, International Collaborative Laboratory of 2D Materials for Optoelectronics Science and Technology of Ministry of Education, College of Physics and Optoelectronic Engineering, Institute of Microscale Optoelectronics, Shenzhen University, Shenzhen518060, P. R. China
Xie Ni
Collaborative Innovation Center for Optoelectronic Science & Technology, International Collaborative Laboratory of 2D Materials for Optoelectronics Science and Technology of Ministry of Education, College of Physics and Optoelectronic Engineering, Institute of Microscale Optoelectronics, Shenzhen University, Shenzhen518060, P. R. China
Nie Guohui
Collaborative Innovation Center for Optoelectronic Science & Technology, International Collaborative Laboratory of 2D Materials for Optoelectronics Science and Technology of Ministry of Education, College of Physics and Optoelectronic Engineering, Institute of Microscale Optoelectronics, Shenzhen University, Shenzhen518060, P. R. China
Jiao Jinqing
Key Laboratory of Marine Chemistry Theory and Technology (Ocean University of China), Ministry of Education, Qingdao, 266100, China
Qiu Meng
Key Laboratory of Marine Chemistry Theory and Technology (Ocean University of China), Ministry of Education, Qingdao, 266100, China
Zhang Han
Collaborative Innovation Center for Optoelectronic Science & Technology, International Collaborative Laboratory of 2D Materials for Optoelectronics Science and Technology of Ministry of Education, College of Physics and Optoelectronic Engineering, Institute of Microscale Optoelectronics, Shenzhen University, Shenzhen518060, P. R. China
Mesoporous carbon spheres (MCSs) are widely used in the field of pollutants adsorption, energy storage and various biomedicine applications such as targeted delivery vector, phototherapy sensitizers, bioimaging contrast agents, etc. Current synthetic strategies including soft templating and hard templating methods generally have the limits of using expensive surfactants or lack of control over the pore structures. Therefore, the complex and uncontrollable pore structures limit its further clinical application. Herein, we proposed a new synthetic strategy to control the uniformity of pore channel arrangement in MCSs which can modulate the photonic property and the corresponding light controlled drug release property in intelligent drug delivery. The as obtained MCSs with relative uniform pore channel arrangement and long pore channels are demonstrated to have the best NIR light-induced drug release performance. This work provides not only new synthetic method to modulate pore structure characteristics and biophotonic property of MCSs, but also uniform MCSs as novel delivery platforms with advanced controlled release performance.
