Relationship between lens morphology and axial length in adolescents

Abstract

Objective To investigate the change rules of lens by analyzing the relationship between lens morphology and axial length in adolescents. Methods A total of 285 adolescents (6~18 years old, 570 eyes) who visited our ophthalmological department from May to June 2020 were enrolled in this study. Diopter, axial length, keratometry and lens parameters were obtained by optometry after cycloplegia, optical biomimetry (IOL Master) and anterior segment optical coherence tomography (CASIA2), respectively. The subjects were divided into 3 age groups (6~10, 11~14 and 15~8 years), and were also assigned into 3 groups in accordance with their equivalent spherical specularity: hyperopia, emmetropia and myopia groups. One-way analysis of variance was adopted to compare lens parameters among different age and refractive groups, and their relationships with axial length were analyzed with Pearson correlation analysis and linear regression analysis. Results In different age groups, statistical differences were observed in the radius of anterior surface curvature and the diopter of lens (P < 0.05); And similar results were seen in above 2 parameters and in the thickness and diameter of lens among different refractive groups (P < 0.05). The curvature radius of the anterior and posterior surface, diopter, and thickness and diameter of lens were all significantly correlated with the axial length of eye in different age groups and refractive groups (P < 0.001). In the hyperopia, emmetropia and myopia groups, with the increase of every 1 mm in ocular axis, the radius of anterior surface curvature was increased by 1.19, 1.04 and 0.58 mm; the radius of posterior surface curvature was increased by 0.41, 0.38 and 0.30 mm, the diopter was decreased by 1.68 D, 1.44 D and 0.98 D; the thickness was reduced by 0.076, 0.091 and 0.059 mm, and the diameter increased by 0.3, 0.23 and 0.24 mm, respectively. Conclusion The disparity of lens parameters among different ages and refractive states in adolescents is mainly caused by the diversity of axial length. The morphological changes of the lens are coordinated with the growth of axial length, but the changes will be decreased with the growth

Keywords

• ametropia
• axial length
• lens refractive power