Nature Communications (Jun 2018)

Global pairwise RNA interaction landscapes reveal core features of protein recognition

  • Qin Zhou,
  • Nikesh Kunder,
  • José Alberto De la Paz,
  • Alexandra E. Lasley,
  • Vandita D. Bhat,
  • Faruck Morcos,
  • Zachary T. Campbell

DOI
https://doi.org/10.1038/s41467-018-04729-0
Journal volume & issue
Vol. 9, no. 1
pp. 1 – 10

Abstract

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RNA–protein interactions often depend on the recognition of extended RNA elements but the identification of these motifs is challenging. Here, the authors present a global integrated approach to analyze RNA–protein binding landscapes, mapping extended RNA interaction motifs for four RNA-binding proteins.